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Interestingly, many of the pathways identified in this study to be altered by metformin in both functional and transcriptomic analysis have been previously implicated in the cellular radioresponse

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[PMC free article: PMC3614115] [PubMed: 20857257] (Retrospective analysis of 435 cases of acetaminophen overdose managed in the Northern California Kaiser Permanente system between 2003 and 2008 found similar hospital length of stay with iv as with oral N-acetylcysteine therapy